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动物学研究 1992
OBSERVATIONS ON NEW CELL LINE OF Indian muntjac TRANSFORMED WITH MNNG
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Abstract:
Lung fibroblast line of Indian muntjac (KIZ-7901) was transformed with MNNG (N-Methyl-N-nitro-N-nitrosoguanidine). The transformed Indian mu-ntjac: cells (KIZ-8401) possessed the new karyotype with cbromorsome number of 8 in male and polyploid. The morphology and cell cycle as well as mitotic index in MNNG-transformed muntjac cells were different from diploid cell line of Indian muntjac (KIZ-7901). Moreover, the MNNG-transformed muntjac cells possessed colony-forming capacity in vitro.