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中国生物工程杂志 2008
Advances and Characters in the Expression of Foreign Proteins in Bacillus Megaterium
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Abstract:
Bacillus megaterium is a potential kind of genetic engineering host which can secrete, Now it is used in industry and academic fields. It has some advantages, e.g: protein yields are exceptionally high; heredity is very stable; production can be secreted; zymotechnique is mature and so on. This article has summarized the advantages of Bacillus megaterium ,the characteristics of the expression vector, the methods of transformation of Bacillus megaterium,the expression of foreign proteins, and the strategies of high-level expression, meanwhile looked into the future of the Bacillus megaterium.