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OALib Journal期刊
ISSN: 2333-9721
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遗传  1997 

Effects of Lowering PARP Enzyme Activity on the Stable Integration of the Exogenous Gene
降低PARP酶活性对外源基因稳定整合的影响 Effects of Lowering PARP Enzyme Activity on the Stable Integration of the Exogenous Gene

Keywords: PARP enzyme,Inhibitor,Stable integration,Transient expression
PARP酶,抑制剂,整合作用,瞬时表达

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Abstract:

In this study, the effect of lowering PARP activity on the transfection of cultured cells with foreign genes was evaluated. The results indicated that PARP enzyme involved in the stable integration of foreign genes into the host genome. However, inhibition of PARP activity exhibited no effect on both the uptake into the cells and the expression of the foreign genes.

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