A Study of the Distribution about Genotype and Allele Frequencies of T102C Polymorphism in the 5-HT2a Receptor Gene in Chinese Han Population in Shanghai
上海地区汉族人5-HT2a受体基因T102C多态性的基因频率分布 A Study of the Distribution about Genotype and AlleleFrequencies of T102C Polymorphism in the 5-HT2a Receptor Gene inChinese Han Population in Shanghai

To investigate the distribution about genotype and allele frequencies of T102C polymorphism in the 5-HT2a receptor gene in Chinese Han population, the genotypes and alleles of 226 healthy person were examined with Restriction Fragment Length Polymorphisms(RFLPs) technique The genotype frequencies are as follows: A1/A2=0 5044,A1/A1=0 2965,A2/A2=0 1991,respectively, and the allele frequencies are as follows: A1=0 5487,A2=0 4513, respectively The heterozygosity(H) is 0 5044, the expected heterozygosity(h) is 0 4953, and the Polymorphism Information Content(PIC) is 0 3726 Our findings suggest that the T102C polymorphism in 5-HT2a receptor gene may have suitable information to be used for association study or forensic identification