The Influence of Novelty Seeking Behavioral Trait on Ethanol Induced Stimulatory Effects in Mice
小鼠新颖寻求特质对酒精的运动激活效应的影响

Novelty seeking or sensation seeking is often associated with susceptibility to substance abuse.In preclinical studies,high and low novelty seeking animals show different sensitivities to locomotor stimulating,rewarding and reinforcing effects of drugs of abuse,such as cocaine,amphetamine and morphine.It is well known that chronic alcohol consumption can result in alcoholism;however,little is known about the relationship between novelty seeking behavioral trait and propensity to alcoholism.The present study...