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心理学报 2011
Hippocampal NMDA Receptor is involved in Chronic Stress Induced Depressive-Like Behaviors via SP-NK1 Receptor Pathway
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Abstract:
Stressors markedly influence central neurochemical and hormonal processes and thus play a pivotal role in the occurrence of depressive illnesses.As the center for stress response and the potential target for stressful provocation,hippocampus is becoming a focus in depression research.Although a large number of behavioral paradigms have been proposed as animal models of depression,only a few are considered as potentially useful research tools with sufficient validity.The most accepted one is chronic unpredic...