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Advances in microbial eco-systems metabolic network study
微生物生态系统代谢网络研究进展

Keywords: Microbial eco-system metabolic network,mixed-culture,high-throughput techniques,computational biology
关键词:微生物生态系统代谢网络,共培养技术,高通量技术,计算生物学

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Abstract:

Abstract: Microbial eco-systems metabolic networks (MEMNs) are ubiquitous in nature and are the major drivers of biosphere processes. Here we try to define MEMNs and describe their significances in microbial ecology studies. We also review recent progresses and approaches of MEMNs including highlights of the major discoveries in these studies based on mixed-cultures, high-throughput sequencing and microarray data, computational approaches, and metabolic reconstruction. In addition, we discuss the potential shortcomings of current approaches and propose that the time is ripe to study the energy-based microbial metabolic networks in bioremediation systems, especially under the anaerobic conditions, which will reclaim the wastes to resources.

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