DELECTION OF HUMAN PAPILLOMAVIRUS DNA IN COLORECTAL CARCINOMA
检测结直肠组织中人乳头瘤病毒DNA的研究

Piopsy spesmens specimens from colorectum of 123 pahents were analysised for human papiIlomavirus (HPV) by polymerase chain reachon (PCR). We used genera consensus primers and type-specific primers (16,18). HPV DNA was delected in 14.6% of Piopies-There were two of 17 in normal (3.3%), colorechhs and inflammatory polyps, three of 17 in papillate adenomas (17.6%) and thirteen of 35 in colorectal. Detection rate of HPV DNA in normal, adjacent carcinoma and carcinoma were 13 / 35 (37.1%), 2 / 35(5.7%) and 1 / 35(2.9%)respechvely. HPV was predominahy type 18 in colorectal carcinoma. The inflammatory rate is higher in rectum and left colon than right colon.