Study of Correlationship between Calcium Antagonism and Protection of Optic Nerves in Traditional Chinese Medicine
中药钙拮抗作用与视神经保护的相关性研究

The apoptosis of retinal ganglion cells and the damage of optic nerves in glaucoma have their common passage, but antagonist drugs with calcium are able to block up the apoptosis of retinal ganglion cells by many links, thus playing a role of protecting optic nerves. Therefore, the authors of this article suggest that there must be a given correlationship between calcium antagonism and the protection of optic nerves. In their studies the authors chose Erigeron breviscapus as an example to screen its effective components by the technology of 45Ca isotope and took in vitro constant and high -pressure experiment of retinal ganglion cell culture to investigate whether there exists the correlationship between the calcium antagonism of this herb and the protection of optic nerves. By summarizing the results of the experiment from several aspects and preliminarily analyzing their correlationship it is demonstrated that there is a best correlationship between the calcium antagonism of the effective components of Erigiron breviscapus and the protection of optic nerves.