Development of Mesoscopic Simulation Study on Nonionic Block Copolymer Surfactants
嵌段共聚物类非离子表面活性剂的介观模拟研究进展

Nonionic block copolymer surfactants, with low stimulation and low toxicity, have been widely used as pharmaceutical excipients. The study on surfactants is mainly by experiments. But this method is difficult to study on the solubilization mechanism of surfactants. Mesoscopic simulation, with shorter period, lower cost, which was benefit for the study of mechanism and could provide guidelines for experiments and applications, was favored by researchers. Recent years, lots of studies have been carried out on nonionic block copolymer surfactants. This paper reviewed the mesoscopic simulations on nonionic block copolymer surfactants, aiming to provide an effective method for the study on mechanism and application of nonionic block copolymer surfactants.