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世界科学技术-中医药现代化 2012
Optimization of Extraction Technology of Herba Epimedii Dispensing Granules by Orthogonal Experiment
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Abstract:
This study was aimed to optimize the extraction process of Herba Epimedii dispensing granules. The extraction process of Herba Epimedii dispensing granules was optimized through orthogonal experiment while the content of general flavone and icariin. And the yield of dry extract was adopted as marks. And influences of solvent dosage, extraction time and extraction times were studies. The results showed that optimized extraction conditions of Herba Epimedii dispensing granules were determined as follows. The material was added 13 times amount of water, soaked for 0.5 h and extracted for 1 h at the first time. And for the second time, 10 times amount of water were added, and extracted for 1 h. It was concluded that the extraction process is efficacious for general flavone and icariin extraction. The method is suitable for the standardized production technology of Herba Epimedii dispensing granules.