Health-related Quality of Life in Diarrhea-Irritable Bowel Syndrome Patients and Its Influence Factors
腹泻型肠易激综合征生存质量状态及其影响因素分析

This study was aimed to investigate the quality of life (QOL) in diarrhea-irritable bowel syndrome (D-IBS) patients and its influence factors. The Irritable Bowel Syndrome Specific Quality of Life Scale (IBS-QOL) was used in the QOL evaluation among 68 patients. Then, healthy subjects were compared with, from anxious (DY), conduct disorder (IN), body concept (Bl), health worries (HW), picky (FA), social function (SR), sex (Sx) and interpersonal (RL). The QOL was analyzed from six factors, including sex, age, education, disease duration, severity of symptoms, anxiety and depression. The results of IBS-QOL scores showed that eight directions, especially in FA, HW, DY, IN, among IBS patients were significantly lower than those in healthy people (P < 0.01). There was no significant difference between male and female (P > 0.05). Except RL, there are no significant differences in each age group (P > 0.05). Patients with different educational level have different point (P < 0.05). There was no significant difference between disease duration (P > 0.05). There was significant difference in the symptom severity (P < 0.01). Patients with different anxiety and patients with depression both have different point on QOL (P < 0.01). In IN, Bl, FA, SR, anxiety and depression in patients with integral low-exist. Gender and disease duration have no correlation to the total score of QOL. There are negative correlation between the age, symptom severity, anxiety scale scores, depression scale scores and QOL. Education level and QOL were positively correlated. It was concluded that QOL decreases in D-IBS patients. The main influence factors are educational level, severity of symptoms and mental status. The influence of sex and age to IBS-QOL is still in dispute. The disease duration does not affect the QOL of patients.