Trends in Studies on Chemical Modification and Biomedical Applications of Fullerenes
富勒烯化学修饰与生物医学应用研究进展(Trends in Studies on Chemical Modification and Biomedical Applications of Fullerenes)

Due to their unique structure and physical and chemical properties, fullerene and its derivatives have a wide range of potential applications in biomedical field. They have many advantages in cell protection and antioxidant properties, antibacterial activity, antiviral activity, drug delivery and anti-tumor activities. The solubility of C60 in polar solutions is very low, which has been the major obstacle in the development of biomedical field. The increasingly industrial production and application of fullerenes has raised several questions about their toxicity and related mechanism. In this paper, biomedical applications of fullerenes have been highlighted, and their chemical modification and toxicity studies have been reviewed as well.