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生物物理学报 2004
THE CHANGES OF THE MEMBRANE SHEAR ELASTIC MODULUS AND VISCOSITY OF RETICULOCYTES IN THE COURSE OF TURNING INTO ERYTHROCYTES
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Abstract:
To study the regularities of reticulocyte's membrane shear elastic modulus (E) and membrane viscosity (Um), a model of anemia in rabbits induced by injection of antibody was established. Using a new ektacytometry, the small deformation index (DI)d and the half-time (t0.5) for deformation relaxation of the reticulocytes under the abnormal physiological conditions were measured. (DI)d and t0.5 were respectively put into the reticulocyte's formula and Um formula when calculated the membrane shear elastic modulus and the membrane viscosity, The value of E and Um in the process of reticulocytes changing into erythrocytes in vivo for 72 h was got. It was found that the membrane shear elastic modulus and membrane viscosity decreased in this process of changing. This finding may have some basic theoretical and clinical significance.