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生物物理学报 1994
THE MODEL OF SUBSTRATE INIERACTION WTTH TRICHOSANTHIN BY COMPUTER GRAPHIC SIMULATION
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Abstract:
A model of substlate interaction with Trichosanthin, a RIP,, was established. Atetlaribenuclootide GAGA was chosen as the subehate analogue. Using this model, a possiblemechanism of N-glycosidase achvity of Race as well as the subetrate specificity wasinterpretal in agreement with some bincheemical resuults. The alteration in activity of somemutants could also be well explained.