STUDIES ON THE SIGNALING PATHWAY OF CpG ODNs ACTIVATING proPO SYSTEM IN CHINESE MITTEN CRAB ERIOCHEIR SINENSIS
CpG寡脱氧核苷酸触发中华绒螯蟹酚氧化酶原系统信号传导途径的研究

Prophenoloxidase system(proPO system) plays a key role in the natural immune response of Crustacean animals,but the signal transduction pathway of proPO system is rarely reported.CpG-oligodeoxynucleotides(CpG-ODN) is synthetic oligodeoxynucleotide containing CpG motif that could simulate the bacterial DNA with immunostimulatory activity.Many studies has proved that it is a kind of good non-specificity immunostimulants and specific immunology adjuvant.CpG ODNs could stimulate the proPO system in haemocytes o...