The effects of sodium perchlorate on the liver of Molly Fish (Poecilia sphenops, Cyprinidae, Teleostei)

Adult male molly fishes were reared up to ten days in control water or in water containing sodium perchlorate at concentrations of 1, 5, 25 and 125 ppm. Remarkable steatosis, fibrosis, hyperemia and necrosis were distinguished in parallel with increasing sodium perchlorate concentrations. The striking cellular damages were observed especially in 25 and 125 ppm sodium perchlorate exposed animals. The exposition to 25 ppm sodium perchlorate induced hepatocellular breakdowns and nuclear polymorphism. In 125 ppm sodium perchlorate exposed fish, hyperemia and widened necrotic areas were discovered. The results were evaluated as being the first documentation of histopathological effects of sodium perchlorate on teleost liver.