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PLOS ONE  2012 

Angiogenic Factors Stimulate Growth of Adult Neural Stem Cells

DOI: 10.1371/journal.pone.0009414

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Abstract:

The ability to grow a uniform cell type from the adult central nervous system (CNS) is valuable for developing cell therapies and new strategies for drug discovery. The adult mammalian brain is a source of neural stem cells (NSC) found in both neurogenic and non-neurogenic zones but difficulties in culturing these hinders their use as research tools [1], [2], [3], [4], [5], [6].

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