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Desarrollo, impacto y eficacia de la vacuna conjugada contra Streptococcus pneumoniae en América Latina

DOI: 10.4067/S0370-41062006000400002

Keywords: streptococcus pneumoniae, vaccine, serotype.

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Abstract:

streptococcus pneumoniae is a common nasopharinx colonizer, responsible of many invasive diseases, especially among children under 5 years-old, with the highest mortality in those less than 2 years-old. the study of antigenicity of streptococcus pneumoniae capsule lead to the production of vaccines, beginning with polysaccharides vaccine (uneffective among infants), and after the conjugated vaccine (97.4% effectiveness with 4 doses). based on the frequencies of the circulating serotypes in different countries in latin america, the data shows an intermediate success with the 7-valent vaccine and better coverage with 11-valent. vaccination against streptococcus pneumoniae might be a very important public health measure in our continent

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