Alteraciones urinarias menores como indicadores de afecciones en el injerto renal

a prospective study was conducted in kidney transplants and biopsies were performed among patients with minor urinary disorders, such as microhematuria, mild proteinuria (0.3-0.7 mg/min) and microhematuria plus mild proteinuria, for at least 3 months in a row, in the absence of affections justifying them and of urinary infection. l8 biopsies were performed. in 1 patient the result was normal; 5 presented chronic graft nephropathy (27.3 %); 4, iga nephropathy (22.5 %); 1, membranous nephropathy (5.5 %) and 1, sch？len-henoch purpura nephritis (5.5 %). it was proved that these glomerular affections were recurrent of the base disease. in other patient, it was detected as a de novo glomerulonephritis, segmental and focal glomerulosclerosis. the acute rejection 1-a and the toxicity of cyclosporin were detected in 2 and 3 patients, respectively. the histological study was correlated with the urinary manifestation.