Enfermedad de Creutzfeldt-Jakob en un paciente interpretado como encefalitis por herpes simple

this is the case of a patient presenting with creutzfeldt-jakob disease with an initial presumptive diagnosis of herpes-simplex encephalitis started with behavioral disorders, aggression, visual hallucinations and a progressive loss of vision, worsening in a gradual way, non-specific unintentional movements and prostration status, left hemi-body tonic-clonic convulsions, homolateral paresis, a low response to pain with a poor facial expression and inability to locate the nociceptive stimulus and a light nuchal stiffness. microbiologic studies were conducted for a virology screening including herpesvirus, bacteria and fungi, as well as, cytochemistry of cerebrospinal fluid with normal results, in electroencephalogram appeared alterations related to an asymmetric paroxysmal activity. patient evolved with torpidity and died. anatomic-pathologic studies result of optical microscopy is showed.