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Jan 04, 2023Open AccessArticle
Objective: To explore the application value of PBL (problem-based learning) combined with CBL (case-based learning) teaching model in the standardized training teaching of hematology clinicians. Methods: Thirty-four subjects in the Hematology Department of the First Affiliated Hospital of Bengbu Medical College from July 2020 to December 2020 were selected and randomly divided into two groups. The control group adopted the traditional teaching method, while the experimental group adopted the com...
Nov 17, 2022Open AccessArticle
The thrombocytopenia associated with cocaine consumption has been well documented]. Severe thrombocytopenia usually occurs within 3 weeks of intravenous or inhaled cocaine abuse. Microangiopathic hemolytic anemia (MHA) associated with cocaine is rare. We would like to report a case of cocaine-induced atypical hemolyticus uremic syndrome. Clinical Observation: this is a 29-year-old Causasian patient, followed in a psychiatric center under duress for 6 years for behavioral disorders, hallucination...
Sep 30, 2022Open AccessArticle
Hemophagocytic Lymphohistiocytosis (HLH) is rare fulminant disease with high mortality. High clinical suspicion is required to diagnose HLH. Malignancy can cause secondary HLH. We reported a case of 45 years old lady with hypertension, presented with bilateral loin pain. On presentation to hospital, she was clinically ill, dehydrated and laboratory parameters showed severe acute kidney injury. CECT abdomen showed huge pelvic mass. Throughout ward admission, she had period of unexplained fever an...
Sep 30, 2022Open AccessArticle
Background: Sickle cell disease is an autosomal recessive genetic disease characterized by a point mutation. In the Democratic Republic of Congo, approximately 40,000 newborns are born with sickle cell disease. Objective: The objective of the study is to determine the predominant reasons for consultation of sickle cell patients at the Center of Mixed Medicine and SS Anemia (CMMASS) in Kinshasa. Methods: This study was conducted at CMMASS. It is a retrospective study carried out on the files of e...
Jun 08, 2022Open AccessArticle
Von Willebrand factor is a multimeric glycoprotein that plays an essential role in platelet-rich thrombi formation under high shear stress. The heterogeneity of Von Willebrand disease (vWD) illustrates the complex physiology of this protein. For women, menstrual patterns and heavy menstrual bleeding are the most frequent disorders within the inherited bleeding disorders population. Pelvic pain due to recurrent hemorrhagic ovarian cyst does not appear to have a higher frequency in the vWD populat...
Aug 19, 2021Open AccessArticle
Introduction: Von Willebrand disease (VWD) is the commonest inherited bleeding disorder worldwide. The prevalence of VWD in African or Nigerian population is however not known. Objective: To determine the prevalence of VWD among apparently healthy youths in Ibadan, Southwestern Nigeria. Materials and Method: This was a descriptive, analytical, cross-sectional study, in which one hundred and eighty-two participants who met the inclusion criteria and who consented to partake in the study were recr...
May 13, 2021Open AccessArticle
Hemophagocytic lymphohistiocytosis (HLH) is an aggressive and life threatening syndrome of excessive immune activation. This condition can be inherited or secondary to other diseases. The therapeutic success is directly related to the rapid diagnosis with the patient who have high clinical suspicious index such as febrile illness with cytopenia, liver enzyme derangement, raised serum ferritin and low fibrinogen levels. Infection is a common trigger both in those with a genetic predisposition and...
Sep 30, 2020Open AccessArticle
Introduction: The diagnosis of sickle cell disease is clinical and biological. It is possible to reduce the morbidity and mortality linked to sickle cell disease thanks to regular clinical and biological monitoring. The objective of this study is to determine the level of knowledge and practices of health providers on the biological diagnosis and biological monitoring of homozygous sickle cell disease in the city of Kindu. Methodology: This is a cross-sectional descriptive study carried out betw...
Sep 23, 2020Open AccessArticle
Low grade B-cell non-Hodgkin lymphoma (LBNHL) is usually slow growing and most often incurable. Case 1: A 47-year-old Malay gentleman was diagnosed with relapsed Stage IV Grade 2 Follicular Lymphoma (Follicular lymphoma international prognostic index, FLIPI 2: intermediate risk). He was initially treated with 6 cycles of standard rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone (R-CHOP) polychemotherapy at first presentation and was in remission for 8 years until he relapse...
Jan 10, 2020Open AccessArticle
Acute promyelocytic leukemia (APL) is a biologically and clinically distinct variant of acute myeloid leukemia (AML), and accounts for 5 to 20 percent of all AML cases. It is a highly curable hematological malignancy with targeted therapy. Patients usually present with symptoms of the complications, typically bleeding. Intracranial bleeding with APL is rarely seen at the presentation, but more common in relapsed cases. APL is a me ...
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