OALib Journal
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Jan 04, 2023Open    AccessArticle

Application of PBL Combined with CBL Teaching Mode in Clinical Training of Hematology Department

Pingping Zhang, Jiajia Li, Meng Wang, Feng Zhang
Objective: To explore the application value of PBL (problem-based learning) combined with CBL (case-based learning) teaching model in the standardized training teaching of hematology clinicians. Methods: Thirty-four subjects in the Hematology Department of the First Affiliated Hospital of Bengbu Medical College from July 2020 to December 2020 were selected and randomly divided into two groups. The control group adopted the traditional teaching method, while the experimental group adopted the com...
Open Access Library J.   Vol.9, 2022
Doi:10.4236/oalib.1109533


Nov 17, 2022Open    AccessArticle

Atypical Shu (PTT) Induced by Chronic Drinking of Cocaine: A Case

Alpha Boubacar Bah, Flahaut Gauthier, Mamadou Saliou Balde, Mamadou Cellou Balde, Gabriel Choukroun
The thrombocytopenia associated with cocaine consumption has been well documented]. Severe thrombocytopenia usually occurs within 3 weeks of intravenous or inhaled cocaine abuse. Microangiopathic hemolytic anemia (MHA) associated with cocaine is rare. We would like to report a case of cocaine-induced atypical hemolyticus uremic syndrome. Clinical Observation: this is a 29-year-old Causasian patient, followed in a psychiatric center under duress for 6 years for behavioral disorders, hallucination...
Open Access Library J.   Vol.9, 2022
Doi:10.4236/oalib.1109486


Sep 30, 2022Open    AccessArticle

An Unusual Case of Ovarian Dysgerminoma Associated with Secondary Hemophagocytic Lymphohistiocytosis (HLH)

Nursofiah Hassan Ali, Anuradha P. Radhakrishnan, Mohd Isnisyam Saaya
Hemophagocytic Lymphohistiocytosis (HLH) is rare fulminant disease with high mortality. High clinical suspicion is required to diagnose HLH. Malignancy can cause secondary HLH. We reported a case of 45 years old lady with hypertension, presented with bilateral loin pain. On presentation to hospital, she was clinically ill, dehydrated and laboratory parameters showed severe acute kidney injury. CECT abdomen showed huge pelvic mass. Throughout ward admission, she had period of unexplained fever an...
Open Access Library J.   Vol.9, 2022
Doi:10.4236/oalib.1109233


Sep 30, 2022Open    AccessArticle

Reasons for Consultation of Sickle Cell Patients at the Center for Mixed Medicine and SS Anemia

Paulin Mulowayi, Berry Bongenya, Ben Bulanda, Elvis Kateba, Steve Kodondi, Christian Vangu, Blezz Nkolomoni, Erick N. Kamangu
Background: Sickle cell disease is an autosomal recessive genetic disease characterized by a point mutation. In the Democratic Republic of Congo, approximately 40,000 newborns are born with sickle cell disease. Objective: The objective of the study is to determine the predominant reasons for consultation of sickle cell patients at the Center of Mixed Medicine and SS Anemia (CMMASS) in Kinshasa. Methods: This study was conducted at CMMASS. It is a retrospective study carried out on the files of e...
Open Access Library J.   Vol.9, 2022
Doi:10.4236/oalib.1109132


Jun 08, 2022Open    AccessArticle

Recurrent Cyst within Willebrand Disease: Place of Surgery?

Meriem Nafidi, Amal Khald, Abderrahim Aboulfalah, Abderraouf Soummani
Von Willebrand factor is a multimeric glycoprotein that plays an essential role in platelet-rich thrombi formation under high shear stress. The heterogeneity of Von Willebrand disease (vWD) illustrates the complex physiology of this protein. For women, menstrual patterns and heavy menstrual bleeding are the most frequent disorders within the inherited bleeding disorders population. Pelvic pain due to recurrent hemorrhagic ovarian cyst does not appear to have a higher frequency in the vWD populat...
Open Access Library J.   Vol.9, 2022
Doi:10.4236/oalib.1108731


Aug 19, 2021Open    AccessArticle

Prevalence of von Willebrand Disease among Nigerian Youths in Ibadan, South-Western Nigeria

Khadijah B. Shonde-Adebola, Wuraola A. Shokunbi, Mukhtar B. Adebola
Introduction: Von Willebrand disease (VWD) is the commonest inherited bleeding disorder worldwide. The prevalence of VWD in African or Nigerian population is however not known. Objective: To determine the prevalence of VWD among apparently healthy youths in Ibadan, Southwestern Nigeria. Materials and Method: This was a descriptive, analytical, cross-sectional study, in which one hundred and eighty-two participants who met the inclusion criteria and who consented to partake in the study were recr...
Open Access Library J.   Vol.8, 2021
Doi:10.4236/oalib.1107789


May 13, 2021Open    AccessArticle

Hemophagocytic Lymphohistiocytosis Secondary to Varicella Zoster with Acute Liver Failure

Satesh Ramasundram, Chong Kah Kian
Hemophagocytic lymphohistiocytosis (HLH) is an aggressive and life threatening syndrome of excessive immune activation. This condition can be inherited or secondary to other diseases. The therapeutic success is directly related to the rapid diagnosis with the patient who have high clinical suspicious index such as febrile illness with cytopenia, liver enzyme derangement, raised serum ferritin and low fibrinogen levels. Infection is a common trigger both in those with a genetic predisposition and...
Open Access Library J.   Vol.8, 2021
Doi:10.4236/oalib.1107367


Sep 30, 2020Open    AccessArticle

Knowledge and Practices of Health Providers on the Diagnosis and Biological Monitoring of Sickle Cell Disease in the City of Kindu, in the East of the Democratic Republic of Congo

Antoine Lufimbo Katawandja, Aimé Abdala Kingwengwe, Etienne Shindano Mwamba
Introduction: The diagnosis of sickle cell disease is clinical and biological. It is possible to reduce the morbidity and mortality linked to sickle cell disease thanks to regular clinical and biological monitoring. The objective of this study is to determine the level of knowledge and practices of health providers on the biological diagnosis and biological monitoring of homozygous sickle cell disease in the city of Kindu. Methodology: This is a cross-sectional descriptive study carried out betw...
Open Access Library J.   Vol.7, 2020
Doi:10.4236/oalib.1106757


Sep 23, 2020Open    AccessArticle

Series of Low-Grade B-Cell Lymphoma: Follicular Lymphoma, Marginal Zone Lymphoma, Waldenstrom Macroglobulinemia and Mantle Cell Lymphoma

Ganesh Kasinathan
Low grade B-cell non-Hodgkin lymphoma (LBNHL) is usually slow growing and most often incurable. Case 1: A 47-year-old Malay gentleman was diagnosed with relapsed Stage IV Grade 2 Follicular Lymphoma (Follicular lymphoma international prognostic index, FLIPI 2: intermediate risk). He was initially treated with 6 cycles of standard rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone (R-CHOP) polychemotherapy at first presentation and was in remission for 8 years until he relapse...
Open Access Library J.   Vol.7, 2020
Doi:10.4236/oalib.1106759


Jan 10, 2020Open    AccessArticle

Acute Promeylocytic Leukemia Presenting as Fatal Intracranial Bleeding in a Rural Setting

Ng Kwang How, Satesh Ramasundram, Naganathan Pillai
Acute promyelocytic leukemia (APL) is a biologically and clinically distinct variant of acute myeloid leukemia (AML), and accounts for 5 to 20 percent of all AML cases. It is a highly curable hematological malignancy with targeted therapy. Patients usually present with symptoms of the complications, typically bleeding. Intracranial bleeding with APL is rarely seen at the presentation, but more common in relapsed cases. APL is a me
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Open Access Library J.   Vol.7, 2020
Doi:10.4236/oalib.1106006


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