OALib Journal
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Mar 31, 2023Open    Access

Anti-Erythrocyte Alloimmunisation in the RH System during Chronic Kidney Disease: Frequency in Patients at the Yaoundé I University Teaching Hospital

Josué Simo Louokdom, Romaric De Manfouo Tuono, Kévine Nelly Dedjo, Prisca Yngrid Meupia Tekam, Foutse Yimta, Peguy Martial Mbianda Tchuessi, Maryline Seuko Njopwouo, Pierre René Fotsing Kwetche
Background: Blood transfusion is a medical procedure that consists in administering total blood or blood products to requiring patients. In case of transfusion incompatibility, de-immunization occurs in the recipient. Objectives: The aim of this investigation was to determine the post-transfusion frequency of anti-erythrocyte alloimmunisation developed in patients with terminal renal disease. Methods: For this purpose, a cross-sectional descriptive study was conducted for two months at the Yaoun...
Open Access Library J.   Vol.10, 2023
Doi:10.4236/oalib.1109932


Mar 01, 2023Open    Access

From Rheumatic Fever to Hemophilia a Major: A Case Report

Najlae Nassiri, Hind Zahiri, Ayyad Ghanam, Aziza El Ouali, Abdeladim Babakhouya, Maria Rkain, Noufissa Benajiba
Severe bleeding after tonsillectomy can lead to airway obstruction and be life-threatening. We report a case of post-tonsillectomy bleeding in a ten-year-old patient with previously undiagnosed hemophilia A, with a history of bleeding after circumcision and hematomas following minimal trauma. He was treated for rheumatic fever because of arthritis and repeated sore throats, for which reason he underwent tonsillectomy. In the postoperative period, the patient presented active bleeding even after ...
Open Access Library J.   Vol.10, 2023
Doi:10.4236/oalib.1109826


Feb 24, 2023Open    Access

Prothrombotic Effect of Serum Uric Acid in Hypertensive Patients

Maria Papavasileiou, Dionysios Aravantinos, Georgios Moustakas, Alexandra Karamanou, Stylianos Patsianis, Andreas Pittaras
Aim: The purpose of this study was to investigate the possible relationship of serum uric acid levels (SUA), in hypertensive patients treated or not, with blood clotting factors. Design and Methods: The study population consisted of 1297 hypertensive patients (46% men) treated (53%) or newly diagnosed untreated (mean age 57.8 years, mean office systolic/diastolic blood pressure -Ms/DBPo-: 147.9/91.6 mmHg, mean office heart rate -mHRo-: 75 ± 11.1 beats per minute, mean body mass index-Mbmi-: 28.2...
Open Access Library J.   Vol.10, 2023
Doi:10.4236/oalib.1109567


Jan 04, 2023Open    Access

Application of PBL Combined with CBL Teaching Mode in Clinical Training of Hematology Department

Pingping Zhang, Jiajia Li, Meng Wang, Feng Zhang
Objective: To explore the application value of PBL (problem-based learning) combined with CBL (case-based learning) teaching model in the standardized training teaching of hematology clinicians. Methods: Thirty-four subjects in the Hematology Department of the First Affiliated Hospital of Bengbu Medical College from July 2020 to December 2020 were selected and randomly divided into two groups. The control group adopted the traditional teaching method, while the experimental group adopted the com...
Open Access Library J.   Vol.9, 2022
Doi:10.4236/oalib.1109533


Nov 17, 2022Open    Access

Atypical Shu (PTT) Induced by Chronic Drinking of Cocaine: A Case

Alpha Boubacar Bah, Flahaut Gauthier, Mamadou Saliou Balde, Mamadou Cellou Balde, Gabriel Choukroun
The thrombocytopenia associated with cocaine consumption has been well documented]. Severe thrombocytopenia usually occurs within 3 weeks of intravenous or inhaled cocaine abuse. Microangiopathic hemolytic anemia (MHA) associated with cocaine is rare. We would like to report a case of cocaine-induced atypical hemolyticus uremic syndrome. Clinical Observation: this is a 29-year-old Causasian patient, followed in a psychiatric center under duress for 6 years for behavioral disorders, hallucination...
Open Access Library J.   Vol.9, 2022
Doi:10.4236/oalib.1109486


Sep 30, 2022Open    Access

An Unusual Case of Ovarian Dysgerminoma Associated with Secondary Hemophagocytic Lymphohistiocytosis (HLH)

Nursofiah Hassan Ali, Anuradha P. Radhakrishnan, Mohd Isnisyam Saaya
Hemophagocytic Lymphohistiocytosis (HLH) is rare fulminant disease with high mortality. High clinical suspicion is required to diagnose HLH. Malignancy can cause secondary HLH. We reported a case of 45 years old lady with hypertension, presented with bilateral loin pain. On presentation to hospital, she was clinically ill, dehydrated and laboratory parameters showed severe acute kidney injury. CECT abdomen showed huge pelvic mass. Throughout ward admission, she had period of unexplained fever an...
Open Access Library J.   Vol.9, 2022
Doi:10.4236/oalib.1109233


Sep 30, 2022Open    Access

Reasons for Consultation of Sickle Cell Patients at the Center for Mixed Medicine and SS Anemia

Paulin Mulowayi, Berry Bongenya, Ben Bulanda, Elvis Kateba, Steve Kodondi, Christian Vangu, Blezz Nkolomoni, Erick N. Kamangu
Background: Sickle cell disease is an autosomal recessive genetic disease characterized by a point mutation. In the Democratic Republic of Congo, approximately 40,000 newborns are born with sickle cell disease. Objective: The objective of the study is to determine the predominant reasons for consultation of sickle cell patients at the Center of Mixed Medicine and SS Anemia (CMMASS) in Kinshasa. Methods: This study was conducted at CMMASS. It is a retrospective study carried out on the files of e...
Open Access Library J.   Vol.9, 2022
Doi:10.4236/oalib.1109132


Jun 08, 2022Open    Access

Recurrent Cyst within Willebrand Disease: Place of Surgery?

Meriem Nafidi, Amal Khald, Abderrahim Aboulfalah, Abderraouf Soummani
Von Willebrand factor is a multimeric glycoprotein that plays an essential role in platelet-rich thrombi formation under high shear stress. The heterogeneity of Von Willebrand disease (vWD) illustrates the complex physiology of this protein. For women, menstrual patterns and heavy menstrual bleeding are the most frequent disorders within the inherited bleeding disorders population. Pelvic pain due to recurrent hemorrhagic ovarian cyst does not appear to have a higher frequency in the vWD populat...
Open Access Library J.   Vol.9, 2022
Doi:10.4236/oalib.1108731


Aug 19, 2021Open    Access

Prevalence of von Willebrand Disease among Nigerian Youths in Ibadan, South-Western Nigeria

Khadijah B. Shonde-Adebola, Wuraola A. Shokunbi, Mukhtar B. Adebola
Introduction: Von Willebrand disease (VWD) is the commonest inherited bleeding disorder worldwide. The prevalence of VWD in African or Nigerian population is however not known. Objective: To determine the prevalence of VWD among apparently healthy youths in Ibadan, Southwestern Nigeria. Materials and Method: This was a descriptive, analytical, cross-sectional study, in which one hundred and eighty-two participants who met the inclusion criteria and who consented to partake in the study were recr...
Open Access Library J.   Vol.8, 2021
Doi:10.4236/oalib.1107789


May 13, 2021Open    Access

Hemophagocytic Lymphohistiocytosis Secondary to Varicella Zoster with Acute Liver Failure

Satesh Ramasundram, Chong Kah Kian
Hemophagocytic lymphohistiocytosis (HLH) is an aggressive and life threatening syndrome of excessive immune activation. This condition can be inherited or secondary to other diseases. The therapeutic success is directly related to the rapid diagnosis with the patient who have high clinical suspicious index such as febrile illness with cytopenia, liver enzyme derangement, raised serum ferritin and low fibrinogen levels. Infection is a common trigger both in those with a genetic predisposition and...
Open Access Library J.   Vol.8, 2021
Doi:10.4236/oalib.1107367


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