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Jul 28, 2025Open    Access

Compatibility and Chemical Stability Study of Bilayer Tablets Pharmaceutical Dosage Form of Aspirin/Clopidogrel as Eudragit L100 Polymer Main Excipient 

Mohammad A. Alassaf,Mohammad F. Mannaa
Due to the multiple diseases in the same patients, and the multiple medications they were taking, it was necessary to formulate medications containing two or more pharmaceutical substances to reduce the patient’s dosage and, as a result, reduce side effects. In this study aspirin and clopidogrel were formulated together in a pharmaceutical dosage form that ensures the chemical and physical stability. By wet granulation method as a first layer for clopidogrel as eduragit L100 as a polymer, which ...
Open Access Library J.   Vol.12, 2025
Doi:10.4236/oalib.1113762


Jul 31, 2024Open    Access

Common Features and the Unique Role of Phosphorus in the Bioproducts ATP as Well as DNA and in Intumescent Flame Retardants

Heinrich Horacek
The natural product Adenosintriphosphate ATP and steel coatings comprise carbohydrate, amine and phosphoric acid. Both exert intumescence, but ATP produces more expanded volume than steel coating. The expansion is determined by Thermomechanical Analysis TMA, the amount of residue by Thermogravimetric Analysis TGA and the evolved or consumed heats by Differential Scanning Calorimetry DSC. Formulas of degradation allow the calculation of decomposition, char formation and expansion. A requirement f...
Open Access Library J.   Vol.11, 2024
Doi:10.4236/oalib.1111661


May 08, 2015Open    Access

Sustainability by Converting Waste Polyurethane Foam into Superior Polyurethane Urea Coatings

Ajay Vasudeo Rane, Mukesh Kathalewar, Vandana Jamdar, V. K .Abitha, Anagha Sabnis
Recycling is a crucial area of research in Green Polymer Chemistry and developments in recycling are driven by environmental concerns, interests in sustainability and desire to decrease dependence on petroleum based materials. Sustainability refers to the development that meets the needs of present without comprising the ability of future generations. Polyurethane foams (PU) are widely used due to their light weight and superior heat insulation as well as good mechanical properties. However, lar...
Open Access Library J.   Vol.2, 2015
Doi:10.4236/oalib.1101533


Apr 30, 2015Open    Access

Gaskets with Expandable Graphite Treated with Nitric, Sulphuric, Phosphoric Acids and Ferric Chloride

Heinrich Horacek
The task was to find out the most appropriate expandable graphite intercalation compound GIC for intumescent seals. The application in fire seals required GICs, which exerted high expansion at low burning rates. Therefore graphite was treated with nitric, sulphuric, phosphoric acids and ferric chloride. Phosphoric acid with its flame retardant properties was the favourite, but graphite treated with it, did not exfoliate, therefore expandable graphite was post treated with phosphoric acid. Elemen...
Open Access Library J.   Vol.2, 2015
Doi:10.4236/oalib.1101297


Oct 06, 2014Open    Access

Skeletally Modified Polyamide Flame Retardant Coatings

J. Sheeba Vinolia, D. Duraibabu, S. Aparna, S. Ananda Kumar
The use of polyamide coatings for electrical applications is restricted mainly because of its inadequate flame retardant behaviour. In order to improve its flame retardant behaviour, polyamide is modified by incorporating phosphorus moiety in its backbone. The structure of the phosphorus and poly amide was confirmed by infrared spectroscopy (FT-IR), NMR, thermo gravimetric analysis (TGA), differential scanning calorimetry (DSC), UL-94 vertical burning tests and char residue tests. From the resul...
Open Access Library J.   Vol.1, 2014
Doi:10.4236/oalib.1100966


Sep 23, 2014Open    Access

Preparation of Poly Aniline by Chemical Ox-idative Method and Its Characterization

Tassew Alemayehu, Diribe Abiebie

The present work reports the oxidative synthesis of poly aniline using K2Cr2O7 as an oxidizing agent and H2SO4 as dopant. The synthesized polymer was characterized by solubility test and UV- visible spectroscopic technique. The synthesized polymer (poly aniline) was insoluble in ethanol, acetone, benzene and water. The absorbance of UV-visible spectra shows two reductive peaks at some wake length. The band ob

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Open Access Library J.   Vol.1, 2014
Doi:10.4236/oalib.1100974


Sep 22, 2014Open    Access

Preparation of PANI-PVA Composite Film with High Conductivity

Xiaohua Wang

The PANI-PVA composite films adopting PVA as the base material and doped with hydrochloride, DBSA, amino sulfonic acid aqueous solution were prepared and their conductivity was compared. Among these PANI-PVA composite films, the conductivity of HCl-PANI-PVA film is the highest. At the same time, the influences of mass ratio between PANI and PVA, acid content, oxidant content, reaction time and drying temperature of film on the conductivity of HCl-PANI-PVA film we

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Open Access Library J.   Vol.1, 2014
Doi:10.4236/oalib.1100849


Sep 19, 2014Open    Access

Synthesis and Characterization of Graft Co-Polymers of Sisal Fiber with Binary Vinyl Monomers

Vijay K. Kaushik, Mukesh Goyal
In this paper morphological transformation of sisal fiber by graft copolymerization with methyl acrylate and its binary mixture with acrylic acid (AAc), vinyl acetate (VA) and n-butyl acrylate (BuA), using FAS-KPS initiator, under influence of microwave radiations has been reported. Optimum reaction conditions for maximum graft yield were kept same as that in case of grafting of principal monomer. Maximum grafting has been observed in case of sisal-g-poly(MA VA). The Graft copolymers thus...
Open Access Library J.   Vol.1, 2014
Doi:10.4236/oalib.1100604


Aug 20, 2014Open    Access

Study of the Effect of Gamma Irradiation on the Mechanical Properties of Polyvinyl Alcohol Based Gelatin Blend Film

Kamol Dey, Sumon Ganguli, Sushanta Ghoshal, Mubarak A. Khan, Ruhul A. Khan

Blend film of polyvinyl alcohol (PVA) based gelatin was prepared by mixing aqueous solutions of both samples. The mixed aqueous solutions of both samples in different ratios (P1, P2, P3, P4 and P5) were then cast onto silicon paper covered glass plate to form film. These films were then irradiated under gamma radiation (60Co) with different intensities (total dose) like 50, 100, 150, 250 and 500 krad to investigate the irradiation effect on the mechanical proper

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Open Access Library J.   Vol.1, 2014
Doi:10.4236/oalib.1100639


Aug 08, 2014Open    Access

Preparation and Fire Test of Intumescent Powder Coatings

Heinrich Horacek

New regulations for hazardous air pollutants drove operations to compliant coatings. Powder coatings were the most popular choice. A screening of intumescent powder coatings was carried out comprising binders like thermoplastics as plasticised polyvinylchloride and polypropylene as well as non-cross linked thermosets as polyurethanes. Intumescence was achieved by addition of the intumescent ingredient bicyclopentaerythritol phosphate, by the intumescent

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Open Access Library J.   Vol.1, 2014
Doi:10.4236/oalib.1100564


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