Attenuation of Tumor Suppressive Function of FBXO16 Ubiquitin Ligase Activates Wnt Signaling In Glioblastoma

Anjali Shiras,Dattatraya Muzumdar,Mohsina Khan

Stromal PTEN Regulates Extracellular Matrix Organization in the Mammary Gland

Anisha M. Hammer,Caitlin E. Jones,Edna Cukierman,Gina M. Sizemore,Jennifer L. Leight,Lisa D. Yee,Michael C. Ostrowski,Samir N. Ghadiali,YouJin Cho

Corrigendum to “CXCR2-Expressing Tumor Cells Drive Vascular Mimicry in Antiangiogenic Therapy–Resistant Glioblastoma” Neoplasia, October 2018, Volume 20, Issue 10, Pages 1070-1082

ASM Iskander,Ali S. Arbab,Bhagelu R. Achyut,Iryna Lebedyeva,Kartik Angara,Mohammad H. Rashid,Ping-Chang Lin,Roni J. Bollag,Roxan Ara,Thaiz F. Borin

Trabectedin Reduces Skeletal Prostate Cancer Tumor Size in Association with Effects on M2 Macrophages and Efferocytosis

A.J. Koh,B.P. Sinder,D. Paige,F.N. Soki,H. Roca,J.D. Jones,L.C. Hofbauer,L.K. McCauley,S. Daignault,S. Thiele,Y. Shiozawa

Genome-Wide Analysis of Head and Neck Squamous Cell Carcinomas Reveals HPV, TP53, Smoking and Alcohol-Related Allele-Based Acquired Uniparental Disomy Genomic Alterations

Christopher I. Amos,Gordon B. Mills,Musaffe Tuna

The SIRT2/cMYC Pathway Inhibits Peroxidation-Related Apoptosis In Cholangiocarcinoma Through Metabolic Reprogramming

Chengfei Jiang,Dehua Tang,Jianlin Wu,Lei Wang,Lei Xu,Lixing Zhou,Mingming Zhang,Robert Gregory Dorfman,Xiaoping Zou,Yida Pan,Yuming Wang,Yuyao Yin

Musashi-1 Enhances Glioblastoma Migration by Promoting ICAM1 Translation

Hsin-I Ma,Jang-Chun Lin,Jo-Ting Tsai,Tsu-Yi Chao,Wei-Hsiu Liu

Extracellular Acidosis Modulates the Expression of Epithelial-Mesenchymal Transition (EMT) Markers and Adhesion of Epithelial and Tumor Cells

Anne Riemann,Mandy Rauschner,Marina Gie？elmann,Oliver Thews,Sarah Reime,Verena Haupt

Ets1 Plays a Critical Role in MLL/EB1-Mediated Leukemic Transformation in a Mouse Bone Marrow Transplantation Model

Jen-Fen Fu,Lee-Yung Shih,Tzung-Hai Yen,Ying-Jung Huang

Conditional Deletion of Eaf1 Induces Murine Prostatic Intraepithelial Neoplasia in Mice

Immune Signature-Based Subtypes of Cervical Squamous Cell Carcinoma Tightly Associated with Human Papillomavirus Type 16 Expression, Molecular Features, and Clinical Outcome

Fangrong Yan,Jiashuo Wang,Jun Gao,Liya Zhang,Liyun Jiang,Wenjun Hu,Xiaofan Lu,Xiaoping Su,Xiaowei Meng,Xinjia Ruan,Yue Zhu,Zhengbao Xu

Overcoming Tyrosine Kinase Inhibitor Resistance in Transformed Cell Harboring SEPT9-ABL1 Chimeric Fusion Protein

Hidetsugu Kawai,Hiromichi Matsushita,Hiroshi Kawada,Kiyoshi Ando,Rikio Suzuki,Yoshiaki Ogawa,Yuka Kitamura

Clodronate-Liposome Mediated Macrophage Depletion Abrogates Multiple Myeloma Tumor Establishment In Vivo

Andreas Evdokiou,Andrew CW Zannettino,Duncan R. Hewett,Elizabeth A. Coulter,Jacqueline E Noll,Kate Vandyke,Khatora S. Opperman,Kimberley C. Clark,Krzysztof M. Mrozik,Nisha Schwarz,Peter I Croucher,Peter J Psaltis

Epigenetically Down-Regulated Acetyltransferase PCAF Increases the Resistance of Colorectal Cancer to 5-Fluorouracil

Qing Robert Miao,Tong Liu,Wenquan Hu,Xiang Wang,Xuedong Fang,Ying Jin,Zhi Fang

A Novel Pyrazolopyrimidine Ligand of Human PGK1 and Stress Sensor DJ1 Modulates the Shelterin Complex and Telomere Length Regulation

Alan E. Bilsland,Andrew Turnbull,Claire J. Cairney,David Jenkinson,David Sumpton,Jon Roffey,Katrina Stevenson,Susan M. Boyd,W. Nicol Keith,Yu Liu

miR-125a-5p Functions as Tumor Suppressor microRNA And Is a Marker of Locoregional Recurrence And Poor prognosis in Head And Neck Cancer

Dat T. Vo,Debabrata Saha,John S. Yordy,John V. Heymach,Lianghao Ding,Michael D. Story,Narasimha Kumar Karanam,Uma Giri

Dual CTLA-4 and PD-L1 Blockade Inhibits Tumor Growth and Liver Metastasis in a Highly Aggressive Orthotopic Mouse Model of Colon Cancer

A Rix,D Doleschel,E Borkham-Kamphorst,E Fiegle,F Kiessling,R Weiskirchen,S Koletnik,W Lederle

The Adiponectin-AdipoR1 Axis Mediates Tumor Progression and Tyrosine Kinase Inhibitor Resistance in Metastatic Renal Cell Carcinoma

Guangxi Sun,Hao Zeng,Haoran Zhang,Jiandong Liu,Jindong Dai,Jinge Zhao,Junru Chen,Mengni Zhang,Ni Chen,Pengfei Shen,Sha Zhu,Xingming Zhang,Xudong Zhu,Yufang Wang,Zhenhua Liu,Zhipeng Wang

SUMOylation of Csk Negatively Modulates its Tumor Suppressor Function

Hailong Zhang,Jian Huang,Jianxiu Yu,Jinzhuo Dou,Nan Cui,Qianqian Yang,Ran Chen,Tianqi Liu,Xian Zhao,Yanli Wang,Yanmin Guo

Telomere Trimming and DNA Damage as Signatures of High Risk Neuroblastoma

Eun Young Yu,Gail J. Roboz,Irene Y. Cheung,Mohamed O. Rabie,Monica L. Guzman,Nai-Kong V. Cheung,Neal F. Lue,Yi Feng

Down-Regulation of S100A8 is an Independent Predictor of PSA Recurrence in Prostate Cancer Treated by Radical Prostatectomy

Alexander Haese,Andreas M Luebke,Asmus Heumann,Christina M？ller-Koop,Christoph Fraune,Claudia Hube-Magg,Cosima G？bel,David Dum,Dominik Hager,Doris H？flmayer,Eike Burandt,Guido Sauter,Hans Heinzer,Hartwig Huland,Jakob Izbicki,Maria Christina Tsourlakis,Markus Graefen,Patrick Lebok,Ronald Simon,Sarah Minner,Stefan Steurer,S？ren Weidemann,Thorsten Schlomm,Till S Clauditz

AsiDNA Treatment Induces Cumulative Antitumor Efficacy with a Low Probability of Acquired Resistance

Fran？oise Bono,Maria Kozlak,Marie Dutreix,Pauline Lascaux,Pierre-Marie Girard,Sergey Alekseev,Sylvain Thierry,Wael Jdey

The SOX4/miR-17-92/RB1 Axis Promotes Prostate Cancer Progression

Bo Han,Haibin Zhou,Hui Liu,Jing Hu,Lin Gao,Lin Wang,Long liu,Mei Qi,Tingting Feng,Wenjie Cai,Xijia Peng,Xinjun Li,Zhen Wu

Induced Chromosomal Aneuploidy Results in Global and Consistent Deregulation of the Transcriptome of Cancer Cells

Amanda B. Hummon,Christina H. Stuelten,Darawalee Wangsa,Georg Emons,Howard H. Yang,Jordi Camps,Kerry M. Bauer,Leigh A. Weston,Lidia Warner,Madhvi Upender,Maria Vila-Casadesús,Markus Brown,Maxwell P. Lee,Philip Brauer,Rüdiger Braun,Thomas Ried,Yue Hu

Notch and mTOR Signaling Pathways Promote Human Gastric Cancer Cell Proliferation

Elise S. Hibdon,Gabriela Wong,Linda C. Samuelson,Nataliya Razumilava,Sumeet Solanki,Theresa M. Keeley,Yatrik M. Shah

Preclinical Studies Support Combined Inhibition of BET Family Proteins and Histone Deacetylases as Epigenetic Therapy for Cutaneous T-Cell Lymphoma

Eric K. Hong,Gary S. Wood,Jean-Phillip Okhovat,Lei Zhao,Youn H. Kim

MicroRNA-130a modulates a radiosensitivity of rectal cancer by targeting SOX4

Huyen Trang Ha Thi,Hye-Yeon Kim,Suntaek Hong,Young-Mi Kim

p85α Inactivates MMP-2 and Suppresses Bladder Cancer Invasion by Inhibiting MMP-14 Transcription and TIMP-2 Degradation

Chao Huang,Chuanshu Huang,Haishan Huang,Jingjing Wang,Jingxia Li,Junlan Zhu,Minggang Peng,Ning Zhang,Qipeng Xie,Xiaohui Hua,Zhongxian Tian

Characterizing Trastuzumab-Induced Alterations in Intratumoral Heterogeneity with Quantitative Imaging and Immunohistochemistry in HER2+ Breast Cancer

Anna G. Sorace,Anum K. Syed,Jennifer G. Whisenant,Ryan Woodall,Thomas E. Yankeelov

Overcoming Resistance to AC0010, a Third Generation of EGFR Inhibitor, by Targeting c-MET and BCL-2

Tingting Li,Wanhong Xu,Wei Tang,Xiaoying Zhang,Yi Sun

Association of CHFR Promoter Methylation with Treatment Outcomes of Irinotecan-Based Chemotherapy in Metastatic Colorectal Cancer

Hee Jin Chang,Hyun Yang Yeo,Ji Yeon Baek,Kyung Hae Jung,Moon Ki Choi,Seung Myung Dong,Sun Young Kim,Yongjun Cha

Homotypic and Heterotypic Activation of the Notch Pathway in Multiple Myeloma–Enhanced Angiogenesis: A Novel Therapeutic Target?

Angelo Vacca,Antonino Neri,Arianna Brevi,Aurelia Lamanuzzi,Daniele Derudas,Domenico Ribatti,Franco Dammacco,Ilaria Saltarella,Lucia Di Marzo,Maria Addolorata Mariggiò,Maria Antonia Frassanito,Maria Teresa Palano,Matteo Bellone,Patrizia Leone,Raffaella Chiaramonte,Roberto Ria,Ruggiero Fumarulo,Vanessa Desantis,Vito Racanelli

Combined Genetic and Chromosomal Characterization of Wilms Tumors Identifies Chromosome 12 Gain as a Potential New Marker Predicting a Favorable Outcome

Hajime Okita,Masahiro Fukuzawa,Masayuki Haruta,Ryuichi P. Sugino,Takaharu Oue,Takehiko Kamijo,Tetsuya Takimoto,Tsugumichi Koshinaga,Yasuhiko Kaneko,Yasuhiro Yamada,Yasuhito Arai,Yukichi Tanaka

An Intratumor Pharmacokinetic/Pharmacodynamic Model for the Hypoxia-Activated Prodrug Evofosfamide (TH-302): Monotherapy Activity is Not Dependent on a Bystander Effect

Cho Rong Hong,Kevin O. Hicks,William R. Wilson

MicroRNA-503-5p Inhibits the CD97-Mediated JAK2/STAT3 Pathway in Metastatic or Paclitaxel-Resistant Ovarian Cancer Cells

Daejin Kim,Ga Bin Park

Tumor Initiation Capacity and Therapy Resistance Are Differential Features of EMT-Related Subpopulations in the NSCLC Cell Line A549

Adrian Ochsenbein,Carsten Riether,Colin Charles Tièche,Elias Daniel Bührer,Gregor Kocher,Kurt Wyler,Laurène Froment,Michael Alex Amrein,Nina Hobi,Patrick Dorn,Primo Sch？r,Ralph Alexander Schmid,Ren-Wang Peng,Rémy Bruggmann,Sabina Anna Berezowska,Sean Ralph Robert Hall,Stefan Weis,Thomas Michael Marti,Yanyun Gao

Prognostic Value of Macrophage Phenotypes in Resectable Non–Small Cell Lung Cancer Assessed by Multiplex Immunohistochemistry

Elin Richardsen,Erna-Elise Paulsen,Lill-Tove Rasmussen Busund,Mehrdad Rakaee,Roy M. Bremnes,Samer Al-Saad,Sigve Andersen,Simin Jamaly,Thomas K. Kilvaer,Tom Donnem

Disrupting Inflammation-Associated CXCL8-CXCR1 Signaling Inhibits Tumorigenicity Initiated by Sporadic- and Colitis-Colon Cancer Stem Cells

Alexandra Aiello,Annamarie Berg,David Liska,Denise Hatala,Edward W. Scott,Emina H. Huang,Henry D. Appelman,Kishan Bellamkonda,L. Alex Molina,Marda L. Jorgensen,Robert C. Fisher,Samaneh K. Sarvestani,Shao Xiang,Sugong Chen,Susmita Chakrabarti

Hypoxia Patterns in Primary and Metastatic Prostate Cancer Environments

Balaji Krishnamachary,Flonne Wildes,Marie-France Penet,Pierre Danhier,Samata Kakkad,Santosh Kumar Bharti,Zaver M. Bhujwalla

Characterizing the Therapeutic Potential of a Potent BET Degrader in Merkel Cell Carcinoma

Andrzej A. Dlugosz,Arul M. Chinnaiyan,Bing Zhou,Doris Mangelberger,Fengyun Su,Ingrid J. Apel,Jae Eun Choi,Jean Tien,Jonathan Gurkan,Kristin Juckette,Marcin Cie？lik,Mishaal Yazdani,Monique E. Verhaegen,Paul W. Harms,Rohit Malik,Rui Wang,Sahr Yazdani,Shaomeng Wang,Xiaojun Jing,Xuhong Cao,Yuping Wang

Blocking Mitotic Exit of Ovarian Cancer Cells by Pharmaceutical Inhibition of the Anaphase-Promoting Complex Reduces Chromosomal Instability

Ahmed El-Balat,Franz R？del,Klaus Strebhardt,Monika Raab,Mourad Sanhaji,Shengtao Zhou,Sven Becker

Comprehensive Investigation of miRNome Identifies Novel Candidate miRNA-mRNA Interactions Implicated in T-Cell Acute Lymphoblastic Leukemia

Anna Lalik,Bronis？awa Szarzyńska-Zawadzka,Jerzy R. Kowalczyk,Krzysztof Ka？wak,Ludomi？a Machowska,Marek Ussowicz,Maria Kosmalska,Ma？gorzata Dawidowska,Micha？ Witt,Monika Drobna,Monika Lejman,Roman Jaksik,Tomasz Szczepański,？ukasz S？dek

Characterization of the ERG-regulated Kinome in Prostate Cancer Identifies TNIK as a Potential Therapeutic Target

Adeline Berger,Birunthi Niranjan,David S Rickman,Gail P Risbridger,Jiangning Song,Lisa G Horvath,Luxi Zhang,Mark A Rubin,Mitchell G Lawrence,Natalie L Lister,Rachel S Lee,Rebecca G Davies,Renea A Taylor,Roger J Daly,Shahneen K Sandhu

Preclinical Prevention Trial of Calcitriol: Impact of Stage of Intervention and Duration of Treatment on Oral Carcinogenesis

Hendrik DeJong,Kristopher Attwood,Mukund Seshadri,Pamela A. Hershberger,Vui King Vincent-Chong

Decoding the Interdependence of Multiparametric Magnetic Resonance Imaging to Reveal Patient Subgroups Correlated with Survivals

Bart RJ van Dijken,Carola-Bibiane Sch？nlieb,Chao Li,Florian Markowetz,Natalie R. Boonzaier,Pan Liu,Shuo Wang,Stephen J. Price,Turid Torheim

Lysyl Oxidase-Like Protein 2 Promotes Tumor Lymphangiogenesis and Lymph Node Metastasis in Breast Cancer

Anji Ju,Chunying Wang,Jie Liu,Qiaoyun Hou,Siran Xu,Yan Fu,Yang Tian,Yongzhang Luo

Single Chromosome Aneuploidy Induces Genome-Wide Perturbation of Nuclear Organization and Gene Expression

Cynthia Hunn,Danny Wangsa,Darawalee Wangsa,Haiming Chen,Indika Rajapakse,Jens K. Habermann,Kerstin Heselmeyer-Haddad,Lena Anthuber,Rüdiger Braun,Scott Ronquist,Thomas Ried,Timo Gemoll,Vishal Koparde

C-terminal α Domain of p63 Binds to p300 to Coactivate β-Catenin

Iyoko Katoh,Kohji Moriishi,Ryu-Ichiro Hata,Shun-ichi Kurata,Yojiro Maehata

Global Reduction of H3K4me3 Improves Chemotherapeutic Efficacy for Pediatric Ependymomas

Barbara Mania-Farnell,Chandra S Mayanil,Charles D James,Chunfa Jie,Gavin Rice,Gordan Gravohac,Guifa Xi,Lindsey Hoffman,Marcelo B Soares,Nicolas K Foreman,Nitin R Wadhwani,Rebecca Lewis,Rintaro Hashizume,Tadanori Tomita,Tatiana Pundy,Ting Lei,Yuping D Li

Characterization of Distinct Populations of Carcinoma-Associated Fibroblasts from Non–Small Cell Lung Carcinoma Reveals a Role for ST8SIA2 in Cancer Cell Invasion

Chang-Qi Zhu,Cédric Zeltz,Dennis Y. Wang,Elena Pasko,Jing Hao,Joella Joseph,Kalpana Venkat,Melania Pintilie,Michael Cabanero,Ming-Sound Tsao,Nadeem Moghal,Quan Li,Roya Navab,Sebastiao N. Martins-Filho,Shingo Sakashita,Tao Wang,Vibha Raghavan,Yu-Hui Wang