%0 Journal Article
%T £¿Existen realmente diferencias cl¨ªnicas entre las distintas concentraciones de clorhexidina?: Comparaci¨®n de colutorios
%A Calsina-Gomis
%A Gloria
%A Serrano-Granger
%A Jorge
%J RCOE
%D 2005
%I Scientific Electronic Library Online
%R 10.4321/S1138-123X2005000400007
%X mouthrinses containing chlorhexidine appear to be the most effective chemical agents in plaque control, with most of them being of 0.12% and 0.20% concentrations. plaque inhibition by chlorhexidine is dose-dependent, which means that comparable effects can be obtained with a smaller volume of a mouthrinse with a higher concentration. the optimum dose of chlorhexidine delivered by mouthrinse, which balances efficacy against local side effects, is considered to be around 20 mg twice a day. better compliance and less tooth staining with shorter rinsing time (30 seconds) is suggested. chlorhexidine at usual concentrations of 0.12% and 0.20% produce side-effects such as extrinsic tooth staining leading to the search of different formulations: chlorhexidine at lower concentrations (0.05%) combined with the incorporation of other active agents to the formulation such as sodium fluoride (0.05%), cetylpyridinium chloride (0.05%) and triclosan is being studied. however, it seems that these lower concentrations are not exempt from the staining effects. furthermore, there are very few long-term studies using these concentrations, so their long-tem effect regarding efficacy and side effects is not known.
%K chlorhexidine
%K mouthrinse
%K concentration.
%U http://scielo.isciii.es/scielo.php?script=sci_abstract&pid=S1138-123X2005000400007&lng=en&nrm=iso&tlng=en