%0 Journal Article
%T Realce por contraste de les£¿es hep¨¢ticas em pacientes com cirrose: estudo cruzado comparativo de dois agentes de contraste para RM realizado em uma ¨²nica institui£¿£¿o. Resultados preliminares
%A Burke
%A Lauren M. B.
%A Vachiranubhap
%A Busakorn
%A Tannaphai
%A Penampai
%A Semelka
%A Richard C.
%J Radiologia Brasileira
%D 2011
%I Col¨¦gio Brasileiro de Radiologia
%R 10.1590/S0100-39842011000300005
%X objective: to prospectively compare full dose gadopentetate dimeglumine (gd-dtpa) with full dose gadobenate dimeglumine (gd-bopta) in the detection of focal hepatic lesions in patients with chronic liver disease on mri. materials and methods: eight patients with hepatic cirrhosis and a strong suspicion for small hepatocellular carcinoma based on prior mri underwent contrast-enhanced mr examinations, one with full dose gd-dtpa and one with full dose gd-bopta. the exams were performed from 72-108 hours apart. two blinded and independent radiologists evaluated images for lesion number, characterization, enhancement, and subjective preference. results: there was no statistically significant difference between the two studies for lesion detection or characterization. there was 18% increased lesion enhancement for gd-bopta, compared to gd-dtpa, of the dominant lesion. both blinded readers subjectively preferred the images using gd-bopta over gd-dtpa in the majority of cases, based on greater lesion enhancement and better edge definition. conclusion: at equivalent full doses, gd-bopta compared similarly with gd-dtpa in the detection and characterization of focal hepatic lesions in patients with chronic liver disease. however, gd-bopta was superior for increased lesion enhancement and subjective preference of the reader.
%K multihance (gd-bopta)
%K magnevist (gd-dtpa)
%K hepatic lesions.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0100-39842011000300005&lng=en&nrm=iso&tlng=en