%0 Journal Article %T Up-Regulation of Hepatitis C Virus Replication and Production by Inhibition of MEK/ERK Signaling %A Jean Ndjomou %A In-woo Park %A Ying Liu %A Lindsey D. Mayo %A Johnny J. He %J PLOS ONE %D 2012 %I Public Library of Science (PLoS) %R 10.1371/journal.pone.0007498 %X Viruses interact with and exploit the host cellular machinery for their multiplication and propagation. The MEK/ERK signaling pathway positively regulates replication of many RNA viruses. However, whether and how this signaling pathway affects hepatitis C virus (HCV) replication and production is not well understood. %U http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0007498