%0 Journal Article
%T Diagnostic ability of barrett's index to detect dysthyroid optic neuropathy using multidetector computed tomography
%A Monteiro
%A M¨¢rio L. R.
%A Gon£¿alves
%A Allan C. P.
%A Silva
%A Carla T. M.
%A Moura
%A Janete P.
%A Ribeiro
%A Carolina S.
%A Gebrim
%A Eloisa M.M.S.
%J Clinics
%D 2008
%I Faculdade de Medicina / USP
%R 10.1590/S1807-59322008000300003
%X objectives: the objective of this study was to evaluate the ability of a muscular index (barrett's index), calculated with multidetector computed tomography, to detect dysthyroid optic neuropathy in patients with graves' orbitopathy. methods: thirty-six patients with graves' orbitopathy were prospectively studied and submitted to neuro-ophthalmic evaluation and multidetector computed tomography scans of the orbits. orbits were divided into two groups: those with and without dysthyroid optic neuropathy. barrett's index was calculated as the percentage of the orbit occupied by muscles. sensitivity and specificity were determined for several index values. results: sixty-four orbits (19 with and 45 without dysthyroid optic neuropathy) met the inclusion criteria for the study. the mean barrett's index values (¡À sd) were 64.47% ¡À 6.06% and 49.44% ¡À 10.94%in the groups with and without dysthyroid optic neuropathy, respectively (p<0.001). barrett's index sensitivity ranged from 32% to 100%, and barrett's index specificity ranged from 24% to 100%. the best combination of sensitivity and specificity was 79%/72% for bi=60% (odds ratio: 9.2). conclusions: barrett's index is a useful indicator of dysthyroid optic neuropathy and may contribute to early diagnosis and treatment. patients with a barrett's index >60% should be carefully examined and followed for the development of dysthyroid optic neuropathy.
%K dysthyroid optic neuropathy
%K multidetector computed tomography
%K graves' orbitopathy
%K visual loss
%K thyroid eye disease.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S1807-59322008000300003&lng=en&nrm=iso&tlng=en