%0 Journal Article
%T Primary cicatricial alopecias: a review of histopathologic findings in 38 patients from a clinical University Hospital in Sao Paulo, Brazil
%A Moure
%A Emanuella Rosyane Duarte
%A Romiti
%A Ricardo
%A Machado
%A Maria Cec¨ªlia da Matta Rivitti
%A Valente
%A Neusa Yuriko Sakai
%J Clinics
%D 2008
%I Faculdade de Medicina / USP
%R 10.1590/S1807-59322008000600007
%X background: scarring alopecias are classified into primary and secondary types according to the initial site of inflammation. in primary scarring alopecias, the hair follicle is the main target of destruction; the term secondary cicatricial alopecia implies that follicular destruction is not the primary pathologic event. aims: to review the histopathologic diagnoses of cases of cicatricial alopecia in order to classify them according to the north american hair research society. patients and methods: patients with biopsy specimens diagnosed as cicatricial alopecia seen from 2000 to 2005 at the dermatologic department of hospital das clinicas, s£¿o paulo university medical school had hematoxylin and eosin, periodic acid-schiff and weigert stained slides reevaluated and sub-typed into different primary cicatricial alopecias. results: thirty-eight cases of primary cicatricial alopecias were reclassified as: chronic cutaneous lupus (17), lichen planus pilaris (4), pseudopelade of brocq (12), folliculitis decalvans (3), dissecting folliculitis (1), and non-specific scarring alopecia (1). in our cases, the methods employed allowed an accurate diagnosis in 12 of 13 cases (92.3%) previously classified as non-specific cicatricial alopecias. conclusions: even in the late, pauci or non-inflammatory phases, an approach with systematic evaluation of a constellation of criteria in routine hematoxylin and eosin stain, periodic acid-schiff and weigert stain allowed for a more accurate diagnosis of cicatricial alopecias.
%K cutaneous lupus erythematosus
%K lichen planus pilaris
%K pseudopelade of brocq
%K folliculitis decalvans
%K dissecting folliculitis.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S1807-59322008000600007&lng=en&nrm=iso&tlng=en