%0 Journal Article %T Is brain banking of psychiatric cases valuable for neurobiological research? %A Schmitt %A Andrea %A Parlapani %A Eleni %A Bauer %A Manfred %A Heinsen %A Helmut %A Falkai %A Peter %J Clinics %D 2008 %I Faculdade de Medicina / USP %R 10.1590/S1807-59322008000200015 %X it is widely accepted that neurobiological abnormalities underlie the symptoms of psychiatric disorders such as schizophrenia and unipolar or bipolar affective disorders. new molecular methods, computer-assisted quantification techniques and neurobiological investigation methods that can be applied to the human brain are all used in post-mortem investigations of psychiatric disorders. the following article describes modern quantitative methods and recent post-mortem findings in schizophrenia and affective disorders. using our brain bank as an example, necessary considerations of modern brain banking are addressed such as ethical considerations, clinical work-up, preparation techniques and the organization of a brain bank, the value of modern brain banking for investigations of psychiatric disorders is summarized. %K brain banking %K post mortem %K schizophrenia %K bipolar disorder %K neurobiology. %U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S1807-59322008000200015&lng=en&nrm=iso&tlng=en