%0 Journal Article
%T Single-Cell STAT5 Signal Transduction Profiling in Normal and Leukemic Stem and Progenitor Cell Populations Reveals Highly Distinct Cytokine Responses
%A Lina Han
%A Albertus T. J. Wierenga
%A Marjan Rozenveld-Geugien
%A Kim van de Lande
%A Edo Vellenga
%A Jan Jacob Schuringa
%J PLOS ONE
%D 2012
%I Public Library of Science (PLoS)
%R 10.1371/journal.pone.0007989
%X Signal Transducer and Activator of Transcription 5 (STAT5) plays critical roles in normal and leukemic hematopoiesis. However, the manner in which STAT5 responds to early-acting and lineage-restricted cytokines, particularly in leukemic stem/progenitor cells, is largely unknown.
%U http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0007989