%0 Journal Article
%T Mst1-FoxO Signaling Protects Na£żve T Lymphocytes from Cellular Oxidative Stress in Mice
%A Juhyun Choi
%A Sangphil Oh
%A Dongjun Lee
%A Hyun Jung Oh
%A Jik Young Park
%A Sean Bong Lee
%A Dae-Sik Lim
%J PLOS ONE
%D 2012
%I Public Library of Science (PLoS)
%R 10.1371/journal.pone.0008011
%X The Ste-20 family kinase Hippo restricts cell proliferation and promotes apoptosis for proper organ development in Drosophila. In C. elegans, Hippo homolog also regulates longevity. The mammalian Ste20-like protein kinase, Mst1, plays a role in apoptosis induced by various types of apoptotic stress. Mst1 also regulates peripheral na£żve T cell trafficking and proliferation in mice. However, its functions in mammals are not fully understood.
%U http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0008011