%0 Journal Article %T Modeling the Time Evolution of the Nanoparticle-Protein Corona in a Body Fluid %A Daniele Dell'Orco %A Martin Lundqvist %A Cecilia Oslakovic %A Tommy Cedervall %A Sara Linse %J PLOS ONE %D 2012 %I Public Library of Science (PLoS) %R 10.1371/journal.pone.0010949 %X Nanoparticles in contact with biological fluids interact with proteins and other biomolecules, thus forming a dynamic corona whose composition varies over time due to continuous protein association and dissociation events. Eventually equilibrium is reached, at which point the continued exchange will not affect the composition of the corona. %U http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0010949