%0 Journal Article
%T Anthrax Lethal Toxin Suppresses Murine Cardiomyocyte Contractile Function and Intracellular Ca2+ Handling via a NADPH Oxidase-Dependent Mechanism
%A Machender R. Kandadi
%A Yinan Hua
%A Heng Ma
%A Qun Li
%A Shu-ru Kuo
%A Arthur E. Frankel
%A Jun Ren
%J PLOS ONE
%D 2012
%I Public Library of Science (PLoS)
%R 10.1371/journal.pone.0013335
%X Anthrax infection is associated with devastating cardiovascular sequelae, suggesting unfavorable cardiovascular effects of toxins originated from Bacillus anthracis namely lethal and edema toxins. This study was designed to examine the direct effect of lethal toxins on cardiomyocyte contractile and intracellular Ca2+ properties.
%U http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0013335