%0 Journal Article
%T Age and Diet Affect Gene Expression Profiles in Canine Liver Tissue
%A Dong Yong Kil
%A Brittany M. Vester Boler
%A Carolyn J. Apanavicius
%A Lawrence B. Schook
%A Kelly S. Swanson
%J PLOS ONE
%D 2012
%I Public Library of Science (PLoS)
%R 10.1371/journal.pone.0013319
%X The liver plays a central role in nutrient and xenobiotic metabolism, but its functionality declines with age. Senior dogs suffer from many of the chronic hepatic diseases as elderly humans, with age-related alterations in liver function influenced by diet. However, a large-scale molecular analysis of the liver tissue as affected by age and diet has not been reported in dogs.
%U http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0013319