%0 Journal Article
%T A Novel Zinc Finger Protein Zfp277 Mediates Transcriptional Repression of the Ink4a/Arf Locus through Polycomb Repressive Complex 1
%A Masamitsu Negishi
%A Atsunori Saraya
%A Shinobu Mochizuki
%A Kristian Helin
%A Haruhiko Koseki
%A Atsushi Iwama
%J PLOS ONE
%D 2012
%I Public Library of Science (PLoS)
%R 10.1371/journal.pone.0012373
%X Polycomb group (PcG) proteins play a crucial role in cellular senescence as key transcriptional regulators of the Ink4a/Arf tumor suppressor gene locus. However, how PcG complexes target and contribute to stable gene silencing of the Ink4a/Arf locus remains little understood.
%U http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0012373