%0 Journal Article
%T Neurodevelopmental Disruption of Cortico-Striatal Function Caused by Degeneration of Habenula Neurons
%A Young-A Lee
%A Yukiori Goto
%J PLOS ONE
%D 2012
%I Public Library of Science (PLoS)
%R 10.1371/journal.pone.0019450
%X The habenula plays an important role on cognitive and affective functions by regulating monoamines transmission such as the dopamine and serotonin, such that its dysfunction is thought to underlie a number of psychiatric conditions. Given that the monoamine systems are highly vulnerable to neurodevelopmental insults, damages in the habenula during early neurodevelopment may cause devastating effects on the wide-spread brain areas targeted by monoamine innervations.
%U http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0019450