%0 Journal Article %T Is There Evidence for Aetiologically Distinct Subgroups of Idiopathic Congenital Talipes Equinovarus? A Case-Only Study and Pedigree Analysis %A Amanda H. Cardy %A Linda Sharp %A Nicola Torrance %A Raoul C. Hennekam %A Zosia Miedzybrodzka %J PLOS ONE %D 2012 %I Public Library of Science (PLoS) %R 10.1371/journal.pone.0017895 %X Idiopathic congenital talipes equinovarus (CTEV) is a common developmental foot disorder, the aetiology of which remains largely unknown. Some aspects of the epidemiology suggest the possibility of aetiologically distinct subgroups. Previous studies consider CTEV as a homogenous entity which may conceal risk factors in particular subgroups. We investigate evidence for aetiologically distinct subgroups of CTEV. %U http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0017895