%0 Journal Article
%T Zinc-Chelation Contributes to the Anti-Angiogenic Effect of Ellagic Acid on Inhibiting MMP-2 Activity, Cell Migration and Tube Formation
%A Sheng-Teng Huang
%A Rong-Chi Yang
%A Hsiao-Ting Wu
%A Chao-Nin Wang
%A Jong-Hwei S. Pang
%J PLOS ONE
%D 2012
%I Public Library of Science (PLoS)
%R 10.1371/journal.pone.0018986
%X Ellagic acid (EA), a dietary polyphenolic compound, has been demonstrated to exert anti-angiogenic effect but the detailed mechanism is not yet fully understood. The aim of this study was to investigate whether the zinc chelating activity of EA contributed to its anti-angiogenic effect.
%U http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0018986