%0 Journal Article
%T Clustering Heart Rate Dynamics Is Associated with ¦Â-Adrenergic Receptor Polymorphisms: Analysis by Information-Based Similarity Index
%A Albert C. Yang
%A Shih-Jen Tsai
%A Chen-Jee Hong
%A Cynthia Wang
%A Tai-Jui Chen
%A Ying-Jay Liou
%A Chung-Kang Peng
%J PLOS ONE
%D 2012
%I Public Library of Science (PLoS)
%R 10.1371/journal.pone.0019232
%X Genetic polymorphisms in the gene encoding the ¦Â-adrenergic receptors (¦Â-AR) have a pivotal role in the functions of the autonomic nervous system. Using heart rate variability (HRV) as an indicator of autonomic function, we present a bottom-up genotype¨Cphenotype analysis to investigate the association between ¦Â-AR gene polymorphisms and heart rate dynamics.
%U http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0019232