%0 Journal Article %T Overexpression of Prothymosin Alpha Predicts Poor Disease Outcome in Head and Neck Cancer %A Satyendra Chandra Tripathi %A Ajay Matta %A Jatinder Kaur %A Jorg Grigull %A Shyam Singh Chauhan %A Alok Thakar %A Nootan Kumar Shukla %A Ritu Duggal %A Ajoy Roy Choudhary %A Siddhartha DattaGupta %A Mehar Chand Sharma %A Ranju Ralhan %A K. W. Michael Siu %J PLOS ONE %D 2012 %I Public Library of Science (PLoS) %R 10.1371/journal.pone.0019213 %X In our recent study, tissue proteomic analysis of oral pre-malignant lesions (OPLs) and normal oral mucosa led to the identification of a panel of biomarkers, including prothymosin alpha (PTMA), to distinguish OPLs from histologically normal oral tissues. This study aimed to determine the clinical significance of PTMA overexpression in oral squamous cell hyperplasia, dysplasia and head and neck squamous cell carcinoma (HNSCC). %U http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0019213