%0 Journal Article %T A reduced dose of darunavir/ritonavir is effective in PI-experienced HIV-infected patients %A Lanzafame %A Massimiliano %A Bonora %A Stefano %A Lattuada %A Emanuela %A Calcagno %A Andrea %A Vento %A Sandro %J Brazilian Journal of Infectious Diseases %D 2011 %I Brazilian Society of Infectious Diseases %R 10.1590/S1413-86702011000500017 %X darunavir (drv) is an hiv-1 protease inhibitor that is used together with a low boosting dose of ritonavir as part of an antiretroviral therapy (art) regimen in treatment-experienced and na£żve hivpositive patients. in na£żve and experienced patients with no drv-mutations, drv is licensed at the dose of 800 mg plus 100 mg of ritonavir once daily. we report our results in seven art-experienced hiv-infected patients, in whom a reduced dose of darunavir/ritonavir (600/100 mg once daily) successfully controlled viral replication %K hiv infections %K pharmacokinetics antiretroviral therapy %K highly active. %U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S1413-86702011000500017&lng=en&nrm=iso&tlng=en