%0 Journal Article
%T Coinfection by HTLV-I/II is associated with an increased risk of strongyloidiasis and delay in starting antiretroviral therapy for AIDS patients
%A Brites
%A C
%A Goyanna
%A F
%A Fran£¿a
%A LG
%A Pedroso
%A C
%A Netto
%A EM
%A Adriano
%A S
%A Sampaio
%A J
%A Harrington Jr
%A W
%J Brazilian Journal of Infectious Diseases
%D 2011
%I Brazilian Society of Infectious Diseases
%R 10.1590/S1413-86702011000100002
%X objective: to compare the clinical characteristics and outcomes of hiv-1-htlv-1 coinfected patients, in bahia, brazil. methods: retrospective, comparative study. results: among a total of 123 consecutive hiv infected patients, 20 men (20.6%) and 6 women (23.1%) had detectable antibodies against htlv-i/ii. the major risk factor associated with coinfection by htlv was intravenous drug use (57.7% of coinfected patient versus 9.2% of htlv seronegative patients, p < 0.0001). coinfected patients had higher absolute lymphocyte counts (1,921 + 762 versus 1,587 + 951, p = 0.03). both groups of patients had similar means of cd4+ and cd8+ cell counts. however, among patients with aids cd4+ cell counts were significantly higher among those coinfected with htlv-i/ii (292 ¡À 92 cells/mm3, versus 140 ¡À 177cells/mm3, p = 0.36). the frequency and type of opportunistic infections were similar for both groups, but strongyloidiasis and encephalopathy were more frequently diagnosed in coinfected patients (p < 0.05). on the other hand, patients coinfected with htlv-i/ii received significantly less antiretroviral therapy than singly infected by hiv-1. conclusion: coinfection by htlv-i/ii is associated with an increased risk of strongyloidiasis for hiv patients. higher cd4 count may lead to underestimation of immunodeficiency, and delay to initiate antiretroviral therapy.
%K hiv
%K htlv-i/ii
%K coinfection strongyloidiasis
%K cd4/cd8.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S1413-86702011000100002&lng=en&nrm=iso&tlng=en