%0 Journal Article
%T Prevalence of estrogen receptor alpha PvuII (c454-397T>C) and XbaI (c454A>G) polymorphisms in a population of Brazilian women
%A Ara¨²jo
%A Karine Lourenzone
%A Rezende
%A Lucas Cunha Dias de
%A Souza
%A Let¨ªcia Soncini
%A Dalto¨¦
%A Renata Dalmaschio
%A Madeira
%A Klesia Pirola
%A Paes
%A Marcela Ferreira
%A Herkenhoff
%A Fernando Luiz
%A Rangel
%A Let¨ªcia Batista Azevedo
%A Silva
%A Ian Victor
%J Brazilian Archives of Biology and Technology
%D 2011
%I Tecpar
%R 10.1590/S1516-89132011000600010
%X the aim of this work was to study the estrogen receptor alpha (ers1) pvuii and xbai gene polymorphisms prevalence in randomly selected women population from rio de janeiro and esp¨ªrito santo states in brazil by polymerase chain reaction restriction fragment lengths polymorphism (pcr_rflp) methodology. it was shown that rio de janeiro women exhibited a significantly different prevalence of xbai polymorphism comparing to espirito santo women. nonetheless, similar prevalence of pvuii polymorphism was found in both women¡äs populations. moreover, a strong linkage disequilibrium was observed between these snps reinforcing the hypothesis of differential pattern of inheritance observed on such populations.
%K polymorphism
%K estrogen receptor
%K brazilian women
%K prevalence
%K linkage disequilibrium.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S1516-89132011000600010&lng=en&nrm=iso&tlng=en