%0 Journal Article
%T Ras Inhibition Induces Insulin Sensitivity and Glucose Uptake
%A Adi Mor
%A Elizabeta Aizman
%A Jacob George
%A Yoel Kloog
%J PLOS ONE
%D 2012
%I Public Library of Science (PLoS)
%R 10.1371/journal.pone.0021712
%X Reduced glucose uptake due to insulin resistance is a pivotal mechanism in the pathogenesis of type 2 diabetes. It is also associated with increased inflammation. Ras inhibition downregulates inflammation in various experimental models. The aim of this study was to examine the effect of Ras inhibition on insulin sensitivity and glucose uptake, as well as its influence on type 2 diabetes development.
%U http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0021712