%0 Journal Article %T Cost-Effectiveness of Opportunistic Screening and Minimal Contact Psychotherapy to Prevent Depression in Primary Care Patients %A Matthijs van den Berg %A Filip Smit %A Theo Vos %A Pieter H. M. van Baal %J PLOS ONE %D 2012 %I Public Library of Science (PLoS) %R 10.1371/journal.pone.0022884 %X Depression causes a large burden of disease worldwide. Effective prevention has the potential to reduce that burden considerably. This study aimed to investigate the cost-effectiveness of minimal contact psychotherapy, based on Lewinsohn's ¡®Coping with depression¡¯ course, targeted at opportunistically screened individuals with sub-threshold depression. %U http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0022884