%0 Journal Article
%T Colinesterasas en sangre total medidas con t¨¦cnica semicuantitativa y en eritrocitos o plasma medidas con t¨¦cnicas cuantitativas: relaciones
%A Carmona-Fonseca
%A Jaime
%J Biom¨¦dica
%D 2007
%I Instituto Nacional de Salud
%X introduction. an equivalence model which allows comparison of blood cholinesterase values, measured by lovibond£¿ (semiquantitative technique), and michel, eqm£¿, monotest£¿ (erythrocyte and plasma cholinesterases) values measured by quantitative techniques is required. objective. the performance of lovibond£¿ (edson tintometric and limperos & ranta techniques) were compared with quantitative techniques. materials and methods. the experimental design was descriptive, cross-sectional, and prospective. from a working population (18-59 years) in valle de aburr¨¢ and near east of antioquia. 827 representative samples were chosen for their lack of exposure to cholinesterase-inhibiting plaguicides and affiliated to the social security system. results. (1) 827 workers were classified by lovibond£¿ in four categories: 821 values with 75% of cholinesterase activity or greater (categories 75, 87.5 and 100%) and 6 with cholinesterase activity smaller than 75%. (2) with each quantitative method, the mean values of erythrocyte and plasmatic cholinesterase corresponding to the four values obtained with lovibond£¿ were statistically different to each other. (3) the mean values of each quantitative technique increased when increased the tintometric method value. (4) lovibond£¿ classified the low enzymatic erythrocyte activity very poorly (61-73%), but the classification of the low enzymatic plasma activity was almost completely in error (94-96%). conclusion. the values of erythrocyte or plasma cholinesterase were adequately estimated by both the quantitative techniques of michel and eqm£¿ and by lovibond, but only when the enzymatic activity is normal. lovibond£¿ , however, had a poor capacity to designate as "low" the values that were low according to the quantitative tests.
%K cholinesterase inhibitors
%K acetylcholinesterase
%K butyrylcholinesterase
%K pesticides
%K organophosphorus compounds
%K epidemiological surveillance
%K colombia.
%U http://www.scielo.org.co/scielo.php?script=sci_abstract&pid=S0120-41572007000200011&lng=en&nrm=iso&tlng=en