%0 Journal Article
%T Wnt signaling: A complex issue
%A HENDRIKS
%A BART
%A REICHMANN
%A ERNST
%J Biological Research
%D 2002
%I Sociedad de Biolog¨ªa de Chile
%R 10.4067/S0716-97602002000200019
%X the development of tissues and organs in multicellular organisms is controlled by the interplay of several signaling pathways that cross-talk to provide positional information and induce cell fate specification. together with other families of secreted factors such as tgf£¿s, fgfs, hedgehog and notch proteins, wnt growth factors are crucially implicated in these processes. here, we will first discuss molecular mechanisms and then consider some biological consequences of wnt signaling
%K wnts
%K frizzled
%K lrp 5/6
%K £¿-catenin
%K apc
%K tcf.
%U http://www.scielo.cl/scielo.php?script=sci_abstract&pid=S0716-97602002000200019&lng=en&nrm=iso&tlng=en