%0 Journal Article
%T Alternative technique for reducing compound waste during intravitreal injections
%A Ribeiro
%A Jefferson Augusto Santana
%A Messias
%A Andr¨¦
%A Scott
%A Ingrid U.
%A Jorge
%A Rodrigo
%J Arquivos Brasileiros de Oftalmologia
%D 2009
%I Conselho Brasileiro de Oftalmologia
%R 10.1590/S0004-27492009000500008
%X purpose: to describe an intravitreal injection technique using a commercially available 29-gauge insulin needle syringe (29gn syringe) and a 21-gauge (g) needle, comparing compound waste associated with this technique application and the one described in ranibizumab (lucentis£¿) kit instructions. methods: ten 0.3 ml doses of distilled water were aspirated using the 29gn syringe and 21g needle (pt technique), and another ten equal doses were aspirated employing the sterilized lucentis£¿ kit (lk technique), which contains a 1ml tuberculin syringe, a 18g needle for compound aspiration and a 30g needle for intravitreal injection. for aspiration using the pt technique, a 21g needle is attached over a 29gn syringe. after compound aspiration, the 21g needle is removed and intravitreal injection is performed using the 29g needle. using a precision balance, the aspiration needles (21g for pt; 18g for lk) were weighed before and after water aspiration and the syringe-needle complexes for injection (29gn for pt; 30g for lk) were weighed before aspiration and after emptying them. the volumes left in the aspiration needles and needle-syringe complexes were estimated by the difference in weight in grams, which were converted to millilitres. results: the mean (¡Àsd) residual volume (ml) of aspiration needles (21g for pt; 18g for lk) was significantly lower with pt technique (0.0034 ¡À 0.0016) when compared to lk tech nique (0.0579 ¡À 0.0011) (p<0.01). the mean (¡Àsd) residual volume (ml) of syringe-needle complexes was significantly lower with pt technique (0.0056 ¡À 0.0011) than with lk (0.0906 ¡À 0.003 ml) (p<0.01). conclusion: the proposed technique is a reasonable alternative for minimizing medication loss during intravitreal injection procedures.
%K angiogenesis inhibitors
%K injections
%K retinal diseases
%K ophthalmologic surgical procedures
%K macular degeneration
%K drug administration routes
%K vitreous body.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0004-27492009000500008&lng=en&nrm=iso&tlng=en