%0 Journal Article
%T Preval¨ºncia de Chlamydia Pneumoniae e Mycoplasma Pneumoniae em diferentes formas da doen£¿a coronariana
%A Maia
%A Irineu Luiz
%A Nicolau
%A Jos¨¦ Carlos
%A Machado
%A Maur¨ªcio de Nassau
%A Maia
%A L¨ªlia Nigro
%A Takakura
%A Isabela Thomaz
%A Rocha
%A Paulo Ricardo de Fernando
%A Cordeiro
%A Jos¨¦ Ant£¿nio
%A Ramires
%A Jos¨¦ Ant£¿nio Franchini
%J Arquivos Brasileiros de Cardiologia
%D 2009
%I Sociedade Brasileira de Cardiologia - SBC
%R 10.1590/S0066-782X2009000600005
%X background: several infectious agents have been investigated since the association between atherosclerosis and infection was demonstrated; however, the results of these studies are contradictory. objective: to test the association between serum titers of anti-chlamydia and anti-mycoplasma antibodies in different forms of acute coronary syndromes (acs). methods: one hundred and twenty-six patients were divided in 4 groups: acs with st- segment elevation (32 patients), acs without st-segment elevation (30 patients), chronic coronary artery disease (30 patients) and blood donors without known coronary disease (34 patients - control group). in the two first groups, serum samples were collected at hospital admission (first 24 hours of hospitalization) and after a 6-month follow-up. in the other two groups, only a basal sample was collected. anti-chlamydia and anti-mycoplasma antibodies were measured by indirect immunofluorescence in all samples. results: significant differences were observed between the basal sample and the one measured after a 6-month follow-up in patients with myocardial infarction with st-segment elevation for chlamydia (650¡À115.7 versus 307¡À47.5, p=0.0001) as well as mycoplasma (36.5¡À5.0 versus 21.5¡À3.5, p=0.0004). the groups with acs had higher anti-chlamydia and anti-mycoplasma serum antibody levels in the basal measurement, when compared to the patients with chronic coronary disease and the control group, but the differences were not statistically significant. conclusion: the present study showed an association between the serum titers of anti-chlamydia and anti-mycoplasma antibodies in the acute phase of patients with unstable angina or myocardial infarction.
%K chlamydophila pneumoniae
%K mycoplasma pneumoniae
%K atherosclerosis
%K coronary artery disease.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0066-782X2009000600005&lng=en&nrm=iso&tlng=en